Medical Safety Information

Important Safety Information

Your safety is our priority. Please read the following information regarding GLP-1 medications prescribed through Imbue Health: Wegovy®, Oral Wegovy®, Zepbound® Vials, and Zepbound® KwikPen

Boxed Warning: Risk of Thyroid C-Cell Tumors

In rodents, Semaglutide and Tirzepatide caused thyroid C-cell tumors. It is unknown whether these medications cause thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans.

Do not use these medications if you have a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Who Should NOT Take GLP-1 Medications

  • Personal or family history of medullary thyroid carcinoma (MTC)
  • Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • Known hypersensitivity or serious allergy to Wegovy® (semaglutide), Oral Wegovy® (semaglutide), Zepbound® Vials or KwikPen (tirzepatide), or any of their ingredients
  • Currently pregnant, planning to become pregnant, or breastfeeding
  • History of pancreatitis
  • Type 1 Diabetes (unless directed by specialist)

Common Side Effects

Most side effects are mild to moderate and often improve as your body adjusts to the medication. Gastrointestinal issues are the most common.

Gastrointestinal

  • • Nausea
  • • Vomiting
  • • Diarrhea
  • • Constipation
  • • Abdominal pain
  • • Heartburn / Acid Reflux

General & Local (Injection)

  • • Fatigue
  • • Headache
  • • Dizziness
  • • Injection site reactions (redness, itching)
  • • Decreased appetite

Serious Side Effects

Stop taking the medication and seek medical attention if you experience:

Signs of Pancreatitis

Severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. The pain may be felt going from your abdomen to your back.

Gallbladder Problems

Pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), or clay-colored stools.

Kidney Problems

Change in the amount of urine, swelling in feet/ankles, or confusion/fatigue (often due to dehydration from vomiting/diarrhea).

Severe Allergic Reaction

Swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.

This is not a complete list of side effects or safety information. Please refer to the full Prescribing Information for each medication and consult your healthcare provider.