Lowest Published Cost · 2026

Cheapest brand-name Zepbound® in 2026

Imbue Health offers the lowest published total cost for brand-name Zepbound® — $29/mo membership + $299/mo medication via LillyDirect = $328/mo all-in.

Last clinically reviewed: May 13, 2026 by the Imbue Health Medical Team

Lowest published total cost

Zepbound® through Imbue Health

Membership

$29/mo

Medication

$299/mo

via LillyDirect

Total all-in

$328/mo

How Imbue compares for brand-name Zepbound®

Estimated monthly cost for the cheapest brand-name Zepbound® path each provider offers.

ProviderMembershipTotal est.
Imbue Health $29/mo$328/mo
WeightWatchers Clinic$74$74–$599/mo
LifeMD$75–$99$198–$598/mo
Found$99$198–$598/mo
GoodRx$119$318–$598/mo
Ro Body Program$74–$149$273–$598/mo
PlushCare$19.99 + $129/visit$149–$1100/mo

Pricing reflects publicly listed rates as of 2026. Totals are estimates of the cheapest brand-name path each provider offers.

What is Zepbound®?

Zepbound® (tirzepatide) Vials is an FDA-approved once-weekly dual GIP/GLP-1 injection with the highest average weight loss of any approved obesity medication — 22% in the SURMOUNT-1 trial, and 20.2% vs 13.7% for semaglutide in the head-to-head SURMOUNT-5 trial. Approved for adults with obesity (BMI ≥30) or overweight (BMI ≥25) with at least one weight-related condition.

  • Format: Once-weekly injection (single-use vial + syringe)
  • Manufacturer: Eli Lilly
  • Fulfilment: LillyDirect
  • Average weight loss: 22% (trial: SURMOUNT-1 / SURMOUNT-5 (Eli Lilly))
Full Zepbound® detail page

Eligibility for Zepbound®

  • Adults 18 and older in all 50 U.S. states and Washington, D.C.
  • BMI ≥30, or BMI ≥25 with at least one weight-related condition (hypertension, type 2 diabetes, dyslipidemia, sleep apnea, cardiovascular disease).
  • No personal or family history of medullary thyroid carcinoma or MEN 2 syndrome.

BMI 25–26.9 is below FDA label thresholds and prescribed at the provider's discretion. BMI under 25 may be considered in cases of abnormal weight gain, at the provider's discretion.

Direct Answer

Start brand-name Zepbound® at $328/mo

$29/mo Imbue membership + $299/mo Zepbound® via LillyDirect. No contracts. Same price the day you start as the day you stop.