Zepbound® cost — every fee, every dose, no surprises
Through Imbue Health, brand-name Zepbound® (tirzepatide) costs $299/mo via LillyDirect plus a $29/mo physician membership — $328–$478/mo (by dose) total. No contracts, no surprise fees, no insurance required.
Last clinically reviewed: June 7, 2026 by the Imbue Health Medical Team
Zepbound® through Imbue Health
Membership
$29/mo
Medication
$299/mo
via LillyDirect
Total all-in
$328/mo
up to $478/mo (higher doses)
Zepbound® cost by dose
Eli Lilly's LillyDirect cash-pay price for each Zepbound® dose, plus Imbue's flat $29/mo membership. This is the full price — there is nothing else to pay.
| Dose | Medication | Total/mo |
|---|---|---|
| 2.5 mg | $299/mo | $328/mo |
| 5 mg | $399/mo | $428/mo |
| 7.5 mgSelf Pay Journey; regular price if not refilled within 45 days | $449/mo | $478/mo |
| 10 mgSelf Pay Journey; regular price if not refilled within 45 days | $449/mo | $478/mo |
| 12.5 mgSelf Pay Journey; regular price if not refilled within 45 days | $449/mo | $478/mo |
| 15 mgSelf Pay Journey; regular price if not refilled within 45 days | $449/mo | $478/mo |
Prices reflect Eli Lilly's published LillyDirect cash-pay rates as of 2026 and may change. LillyDirect cash-pay pricing scales by dose: $299/month (2.5 mg), $399/month (5 mg), and $449/month (7.5–15 mg). The 7.5–15 mg price reflects the Zepbound Self Pay Journey Program and requires refilling within 45 days; otherwise the regular price applies.
Every fee, explained
Membership — $29/month
Covers your licensed-physician evaluation, prescription, and ongoing dose management. Flat fee, billed monthly, cancel anytime.
Medication — from $299/month
Paid to LillyDirect at Eli Lilly's cash-pay rate. Scales by dose (see the table above). Imbue adds no markup.
What you will never be charged
No consultation fee, no enrolment fee, no annual prepay, no shipping charge, and no cancellation penalty. If our physician determines Zepbound® isn't right for you, you aren't charged the membership.
What Zepbound® costs over a year
Most patients begin at the lowest dose and titrate up over the first few months as their body adjusts. Because medication price scales with dose, your monthly cost typically rises during titration and then levels off at your maintenance dose.
≈ $3,936 – $5,736 / first year
From $328/mo at the starting dose to about $478/mo at the highest maintenance dose — membership and medication included.
The $29/month membership is the same the day you start as the day you stop. Want to model your exact path? Try the GLP-1 cost calculator.
What is Zepbound®?
Zepbound® (tirzepatide) Vials is an FDA-approved once-weekly dual GIP/GLP-1 injection with the highest average weight loss of any approved obesity medication — 22% in the SURMOUNT-1 trial, and 20.2% vs 13.7% for semaglutide in the head-to-head SURMOUNT-5 trial. Approved for adults with obesity (BMI ≥30) or overweight (BMI ≥25) with at least one weight-related condition.
- Format: Once-weekly injection (single-use vial + syringe)
- Manufacturer: Eli Lilly
- Fulfilment: LillyDirect
- Average weight loss: 22% (trial: SURMOUNT-1 / SURMOUNT-5 (Eli Lilly))
Eligibility for Zepbound®
Before you weigh the cost, confirm you're a candidate. Zepbound® eligibility through Imbue:
- Adults 18 and older in all 50 U.S. states and Washington, D.C.
- BMI ≥30, or BMI ≥25 with at least one weight-related condition (hypertension, type 2 diabetes, dyslipidemia, sleep apnea, cardiovascular disease).
- No personal or family history of medullary thyroid carcinoma or MEN 2 syndrome.
BMI 25–26.9 is below FDA label thresholds and prescribed at the provider's discretion. BMI under 25 may be considered in cases of abnormal weight gain, at the provider's discretion.
Related pages on Imbue Health
See exactly what Zepbound® will cost you
Transparent, dose-based pricing from $328/mo all-in. No consultation fees, no surprises — the same $29/mo membership every month.