Zepbound®, prescribed online

Get Zepbound® online, the strongest GLP-1 studied

Zepbound® (tirzepatide) posted the highest average weight loss of any FDA-approved medication — up to 22% in 72-week trials. Imbue physicians prescribe it online, shipped from LillyDirect.

Last clinically reviewed: July 16, 2026 by Dr. Prajeet Reddy, MD (Medical Director)

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$29/mo membership · no contracts · no charge if not prescribed

FDA-approved options through Imbue

*Average results from clinical trials of adults with BMI ≥30, or ≥25 with weight-related conditions, alongside diet and exercise. Individual results vary. Medication purchased separately at manufacturer cash-pay pricing.

Why patients choose Zepbound®

Zepbound® works on two hormone pathways at once (GIP + GLP-1), which is why its trial results — up to 22% average weight loss in SURMOUNT-1 / SURMOUNT-5 (Eli Lilly) — lead every FDA-approved option. It's also approved for moderate-to-severe obstructive sleep apnea in adults with obesity.

Through Imbue you choose vials or the pre-filled KwikPen, both from $299/month at LillyDirect cash-pay prices, with the $29/month membership covering all clinical care.

The online process, start to finish

Five minutes of health questions. A physician licensed in your state reviews your history — prescription in as little as 48 hours where appropriate. LillyDirect ships to your door, and your care team manages dose escalation (2.5 mg up to your maintenance dose) from month one.

Frequently asked questions

How much does Zepbound® cost online?

Through Imbue: $299–$449/month by dose via LillyDirect, plus $29/month membership — $328–$478/month all-in.

Vials or KwikPen — what's the difference?

The medication is identical. Vials use a separate syringe (and run the same price); the KwikPen is a pre-filled pen holding four weekly doses. Most patients find the pen more convenient; some prefer vial pricing at specific doses. Your physician helps you choose.

Is Zepbound® better than Wegovy®?

Zepbound® posted higher average weight loss (up to 22%) than Wegovy® (about 15%), and outperformed it head-to-head in SURMOUNT-5. But "better" depends on your health history, tolerability, and preference — that's the physician conversation.

Does insurance cover Zepbound® through Imbue?

Imbue is built for cash-pay simplicity — no insurance needed, no prior authorizations. LillyDirect's cash-pay pricing (from $299/month) is often cheaper than many patients' insurance copays for GLP-1s.

See if you qualify — free

A licensed physician reviews your health history, usually within 48 hours. $29/mo membership only if prescribed — the lowest fee in GLP-1 telehealth. Cancel anytime.